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The Logan System 850BDL Automated Dissolution Sampling System is a modularly designed system for auto mated dissolution sampling. The integral UDT-814 Dissolution Tester can be configured with a drive system co mprising six, seven or eight sampling vessels and spindles. It is used for dissolution testing of a variety of phar maceutical products including tablets, capsules, and transdermal patches. The UDT-814 can be used in severa l configurations that satisfy USP criteria, e.g. rotating baskets (USP I) or paddles (USP II), paddles over disk (U SP V) or rotating cylinders for transdermal applications (USP VI). The UDT-814 is supplied with a built-in heate r/circulator. The heater can be controlled locally by the UDT-814.
The Tablet Dropping Tray accessory automates the process of tablet dropping. It drops the tablets simultaneously, thereby marking the beginning of each test with far greater precision than manual techniques allow. This feature ensures compliance with regulatory requirements. Temperature readings can be taken before, after, and periodically during a run to ensure compliance throughout the test. The automated sampling manifold can be controlled to lower the probes into the vessels. The samples may also be filtered through a membrane or other filters. At each sampling point, the syringe pump takes samples from the vessels and flushes out the sampling lines. After flushing the line, the samples return to the same vessels. This system does not send any sample to waste. The time, speed and temperature will be recorded at the beginning of each test as well as when samples are being taken.
The SYP-8L Syringe Pump module is built-in with the DSC-800 System Controller, which saves lab bench space. The SYP-8L withdraws samples to rinse the line right before each time interval, individual samples are dispensed simultaneously into collection tubes or vials in the SCR-160L Sample Collector. After collecting the samples, SYP-8L does the media replacement, back flushes the filters, and purges all the sampling lines. The DSC-800D System Controller permits quick and easy programming of all parameters and gives the user total flexibility in the use of up to 2 systems simultaneously. Each system can be programmed to control all dissolution parameters, all test method are printed by provided printer.
